Revised 10/2016

MDL 263 - Clinical Chemistry and Instrumentation III (3 CR.)

Course Description

Emphasizes application of chemical theories and principles to perform routines and special chemistries on various types of instrumentations, to evaluate quality control programs, and to associate test results with clinical significance. Lecture 2 hours. Laboratory 3 hours. Total 5 hours per week.

General Course Purpose

The purpose of this course is to prepare students with the knowledge of body chemistry analysis procedures within a clinical chemistry laboratory and the correlation to various disease states. It is designed to produce entry level competence needed to perform at the level of a medical laboratory technician in a sophisticated clinical chemistry laboratory.

Course Prerequisites/Corequisites

Prerequisites: MDL 101, BIO 141, AND BIO 142 with a grade of ���C��� or better. Corequisites: MDL 225 and MDL 263. Corequisite: MDL 260. Students should be enrolled in the first year of the Medical Laboratory Technology AAS degree program or program approval.

Course Objectives

• Upon completing the course, the student will be able to: a) Summarize the process of quality assurance and quality control. b) Recall how precision and accuracy of methods are determined within clinical chemistry. c) Discuss the use of spectrophotometry in the clinical chemistry laboratory. d) Discuss application of various ligand (immunoassay) methods. e) Discuss electrochemical methods of analysis in clinical chemistry, including electrolyte results and acid-base balance f) List the clinically significant carbohydrates and discuss diabetes management g) Discuss the analytes measured in the diagnosis and management of kidney disease h) Correlate increases in enzyme activity, proteins, non-protein nitrogens and bilirubin with disease processes in liver, pancreas, muscle, and other tissues and organs. i) Define cardiac markers and relate to the diagnosis of myocardial infarction (MI). j) Discuss lipid profiles and how they are utilized in minimizing cardiovascular risk. k) Effectively Communicate processes, procedures and results in a multicultural environment

Major Topics to Be Included

a) Concepts of spectrophotometric analysis b) Statistics and quality control/assessment in clinical chemistry Proteins/Enzymes c) Carbohydrates, Electrolytes/Blood, gases NPN, and Renal Function d) Immunochemical (Ligand) assays Lipids/Lipid profile